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Patient
31-year-old male followed for vasculitis (Wegener's granulomatosis) hospitalized for chest pain and major dyspnea; biological assessment: increase in cardiac enzymes and inflammatory syndrome;
Trace
This tracing shows a sinus rhythm, a PQ segment depression in the inferior leads and in V5-V6, a PQ segment elevation in aVR, a narrow QRS, small amplitude Q-waves in the inferior leads and in V5-V6, an elevation of relatively large amplitude from V2 to V6, more moderate in inferior leads, a depression in aVR;
A coronary angiography eliminated the existence of a coronary thrombosis or plaque rupture. A cardiac ultrasound and an MRI led to the diagnosis of myopericarditis (pericardial effusion with large areas of segmental hypokinesia);
Trace
This second tracing, performed the next day, allows assessing the evolving nature of the ECG; quasi-disappearance of the PQ segment depression; persistence of the ST-segment elevation with T-wave inversion from V3 to V5;
A pericardial puncture was performed following the occurrence of compressive signs;
Trace
This tracing was performed 10 days after the occurrence of the first symptoms; the ST-segment is isoelectric with negative T-waves in inferior leads and from V3 to V6 (symmetrical T-waves in V4-V5) and positive in aVR;
Exergue
The electrocardiogram of myopericarditis combines characteristic signs of myocardial inflammation and signs of pericardial inflammation. The latter (PQ segment depression, diffuse transient ST-segment elevation, negative T-waves in a second instance) are generally predominant. The electrocardiographic pattern of myopericarditis often resembles that of myocarditis, the presence of Q-waves, however, potentially suggesting a myocardial involvement.
Wegener's granulomatosis is a necrotizing and granulomatous vasculitis of small vessels with preferential involvement of the respiratory tract. Cardiac involvement is less common with polymorphic clinical presentations. This patient had an episode of relatively severe myopericarditis.