Prolonged PR during exercise

Patient

This 56-year-old patient complaining of dyspnea during exercise and a history of syncopal events underwent implantation of an Adapta dual chamber pacemaker and programmed to a 320-ms PR interval at rest; an episode of rapid ventricular rate was recorded in the device memory.



Trace

Tracing 8a:

  1. programming in AAIR⇔DDDR mode;
  2. recorded 4 minute episode of rapid ventricular rate with AV dissociation (atrial rate at 64 bpm, ventricular rate at 151 bpm);
  3. the rate histogram showed a tachycardia at 150 bpm.

Tracing 8b:

  1. the EGM channel shows simultaneous ventricular and atrial signals; the atrial signal was not sensed because it fell in the post-ventricular atrial blanking period; the episode was, thus, labeled “ventricular high rate” when the latter surpassed 150 bpm;

Comments

The tracings stored in the devices’ memories must be verified. This episode was erroneously labeled by the pacemaker as a rapid ventricular event. Analysis of the EGM suggests that it was a sinus tachycardia in this patient with a long PR interval. This tracing was obtained during effort. The P wave was not sensed as it fell inside the post-ventricular atrial blanking period.
The MVP mode confers a sizable benefit, mainly in patients in sinus rhythm, by markedly decreasing the percentage of ventricular pacing. Its indication is less clear in patients with a long PR interval, particularly if it does not shorten with exercise. It is possible that the exercise-induced dyspnea was entirely or in part due to this prolonged PR interval during effort, from a mechanism similar to the pacemaker syndrome, as a result of simultaneous contraction of the atria and ventricles.
Programming to the DDD mode is probably more appropriate for this patient. One could verify the merit of this programming change by comparing the symptoms experienced by this patient during exercise tests performed in MVP and in DDD modes.

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