PMT

Patient

This 83-year-old man underwent implantation of an Adapta dual chamber pacemaker for complete AV block; 4 days after his discharge from the hospital, he was seen in the emergency department, complaining of palpitations; this tracing was recorded; pacemaker is programmed to the DDDR mode.



Trace

Tracing 5a: recording upon the patient’s arrival; the first channel is lead I of the surface ECG upon which the markers are superimposed, the second channel shows the atrial EGM and the last channel is lead II with the time intervals superimposed;

  1. tachycardia at 110 bpm, the programmed maximum rate; repetition of AS-VP cycles with prolongation of the AV delay (210 ms when the programmed AV delay for spontaneous atrial activity is 120 ms) in order to not surpass the programmed maximum rate; this might be sinus tachycardia (unlikely with the patient at rest), a relatively slow atrial tachycardia or a PMT;

Tracing 5b: an initial interrogation reveals that the anti PMT algorithm is OFF (nominal programming); the algorithm was programmed and the EGM recorded;

  1. same tracing as earlier;
  2. programming of the algorithm;
  3. the diagnosis of PMT is made by the device: 8 consecutive cycles with a VA interval <400 ms [340 ms in this patient: 500 ms (interval VP-VP) – 160 ms (AV delay)]; the VA interval begins with a paced ventricular event, the VA interval ends with a sensed atrial event, and the pacing rate = the maximum programmed rate; anti-PMT intervention: prolongation of the post-ventricular atrial refractory period to 400 ms; atrial events occur during this refractory period and ventricular pacing is not triggered;
  4. atrial pacing after 300 ms to prevent pacing during the atrial vulnerable period and prevent ineffective atrial pacing when delivered during the absolute, natural, atrial refractory period, and ventricular pacing (AP-VP) with a short AV delay; this short AV delay is also a consequence of non competitive atrial pacing (NCAP), which is automatically activated for 1 cycle after the 9th ventricular paced event of an episode of PMT. This function shortens the next paced AV delay to maintain a stable ventricular rate;
  5. interruption of the tachycardia and paced AV rhythm (AP-VP);

Comments

This tracing corresponds to an episode of PMT and highlights some aspects of the Medtronic dual chamber pacemakers function:
1) the algorithm for PMT interruption is not nominal programming; it must, therefore, be programmed on routinely, even in presence of AV block. It is indeed possible, as in this case, that anterograde conduction be interrupted and retrograde conduction preserved. It is also possible that it is absent at rest and present during exercise;
2) the interruption algorithm allows the distinction of sinus tachycardia from atrial tachycardia and PMT. Interruption of the tachycardia is highly in favor of PMT and, in this case, excludes sinus or atrial tachycardia. One needs to block retrograde conduction (VP-AS) only once or the AS-VP sequence to interrupt the tachycardia. The algorithm lengthens the refractory period, atrial retrograde activity no longer initiates an AV delay or a paced ventricular event and the tachycardia is interrupted;
3) in this sedentary 83-year-old patient, the PVARP can be programmed to 360 ms, i.e. longer than the retrograde conduction time. The programming of an AV delay that is relatively short and adaptive to exercise (paced AV delay of 140 ms during exercise) allows the setting of a 2:1 point at 120 bpm.

The programming of anti-PMT interventions is useful only when the retrograde conduction time is <400 ms and, therefore, does not intervene when it is > 400 ms. In such case, PMT remains incessant and the patient’s management is particularly challenging. Strong efforts must be made to avoid all situations that might facilitate the onset of PMT. A possible remedy might be the prescription of a drug that blocks retrograde conduction, which is already slowed, though this measure is rarely effective. Ablation by radiofrequency is another option, though this need is very rare.

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