The efficacy of implantable defibrillators (ICD) in the prevention of sudden death has been confirmed by multiple studies and countless patients. This efficacy, however, depends on the device programming, which varies considerably among medical centers and, within a single center, among the various caregivers. While the different settings may need to be optimized according to the characteristics of each device recipient, such as age, type of heart disease, or primary versus secondary prevention, some general programming rules apply to a majority. A recent article published in Heart Rhythm Journal, written by representatives of the Heart Rhythm Society, European Heart Rhythm Association, Asian Pacific Heart Rhythm Society and Sociedad Latino-Americana of Estimulacion Cardiaca y Electrofisiologia, discusses in depth the data pertaining to 4 important areas of ICD programming, including 1) pacing parameters, 2) sensing and programming zones, 3) programming of shocks and antitachycardia pacing (ATP), and 4) induction of a ventricular arrhythmia at the end of the implantation procedure. They formulated 32 guidelines (class I, IIA, IIB and III) with evidence levels that vary as a function of the number and type of publications (A, B or C). The main document includes an addendum which offers specific recommendations for the programming of the devices made by the 5 main manufacturers. This monograph reviews the main guidelines pertaining to the programming of ICD manufactured by St. Jude Medical, Inc., illustrated by representative tracings highlighting, in particular, the specific characteristics and advantages of the SecureSense™ algorithm included in the most recent devices made by this manufacturer. Parts of this monograph are available in French and English on the Internet site . This freely accessible site reviews the field’s state of the art, going into the details of the specific features of the various pacing, defibrillating and resynchronizing devices. It might also promote exchanges of ideas in discussion forums, enabling the posting of tracings followed by debates on the optimal diagnosis and therapeutic choices. Enjoy the reading